I-385 NORTH: Take I-385 North to Roper Mountain Road - Exit 37. Turn right at the stop light onto Roper Mountain Road. Continue to the next traffic light. The Science Center is the second road on the right.
I-385 SOUTH: Take I-385 S to Roper Mountain Road exit. Turn left at the light onto Roper Mountain Road and go over the bridge. Continue to the second traffic light. The second road on the right is the Science Center.
WADE HAMPTON BLVD (HWY 29): Turn at the Red Lobster onto 291 Bypass South (Pleasantburg Drive) and continue to E. North Street. Turn left onto E. North Street. Turn right onto Pelham Road. Cross Haywood Road. Go about 1 mile and turn right onto Roper Mountain Road Ext. At the dead end turn right onto Roper Mountain Road. The Science Center is 1/2 mile on the left.